Calculation of colistimethate sodium loading dose for low weight patients

Calculation of colistimethate sodium loading dose for low weight patients (under 60kg) ^8,9

Loading dose of colistimethate sodium (million international units) = [4 x patient’s weight* (kg)] / 33

*Use ideal body weight or actual body weight - whichever is lower (refer to SAPG Ideal Body Weight Tables)

If loading dose is less than the recommended maintenance dose then use recommended maintenance dose as loading dose